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Within 28 hours, creatinine levels rose in the test animals, and CT scans showed the presence of dense deposits of calcium oxalate monohydrate in the tubules of the nephrons.
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The researchers surmised that glyoxylic acid was the cause of calcium oxalate-induced nephropathy. At the same time, it has only recently been used in hair straightening products, being regarded as a safer alternative to formaldehyde.